Program Lecturers and Research Collaborators
Program Coordination Committee
Dr. Kollias has pioneered genetic approaches to study the function of TNF in animal models of human diseases and has a long standing expertise in transgenic, gene mutational and knockout technologies, molecular and cell biology and immunology.
Dr. Boumpas' primary clinical and research interests are in the areas of human autoimmunity with emphasis on systemic lupus erythematosus (SLE) and inflammatory arthritis. His work on the treatment of lupus nephritis has shaped immunosuppressive therapy for autoimmune rheumatic diseases internationally.
Dr. Koutsilieris' scientific interests are centered in the areas of Medical Physiology, Molecular Endocrinology, Molecular Oncology, Hormones & Cancer, Bones.
Dr. Gorgoulis' Group focuses on studying the pathways that govern initiation and progression of cancer. His research centers on three main subjects: 1. Mechanisms leading to genomic instability, 2. The role of the DNA damage response (DDR) pathway as an anti-tumor barrier and 3. The role of Cdc6 in cancer progression.
Dr. Kontoyiannis' lab seeks to identify the biological functions of RBPs as epigenetic determinants of specific cellular processes, their effects in signal-dependent re-organization of RNPs, the effect of their dysfunction in life-threatening pathologies and their efficacy as targets for disease monitoring & treatment.
Dr. Panaytou's research focuses on the complex signaling pathways that are activated in mammalian cells upon their stimulation by extracellular stimuli. These processes are very important for the development of many human diseases, and our group investigates these pathways particularly in terms of their role in cancer development.
Dr. Sfikakis has contributed towards the understanding of the pathogenesis of autoimmune rheumatic diseases and improving the therapeutic approach of Systemic Lupus Erythematosus, systemic scleroderma, and Behçet's disease.
Dr. Skoulakis' research focuses on understanding the molecular mechanisms and signaling systems that mediate learning and memory and how these are altered by disease and aging. The Drosophila model is used to study processes essential for learning and memory and to model the action of genes implicated in human neuronal dysfunctions.
Dr. Hatzis' interests focus on investigating Wnt-dependent transcriptional regulation in the intestine and liver and its contribution to normal homeostasis and carcinogenesis, through use of high-throughput techniques, such as ChIP- and RNA-seq and proteomic approaches.
Dr. Kostourou's research focuses on understanding how vascular adhesion controls blood vessel formation and function during development and in cancer, through use of genetically modified mouse models, various ex vivo and in vitro cellular and molecular assays, advanced 4D-live imaging and large-scale proteomics and genomics approaches.
DESPINA SANOUDOU (National and Kapodistrian University of Athens, Medical School)
Dr. Sanoudou's research team focuses on the discovery of novel diagnostic and prognostic markers, the identification of novel therapeutic targets, and the evaluation of chemical compounds against cardiovascular diseases.
CHRISTOFOROS NIKOLAOU (University of Crete, Department of Biology)
Dr. Nikolaou's research interests are related to functional aspects of DNA structure and epigenomic regulation, the evolution of the information content of biological sequences and large-scale properties of genome organization and architecture.
Dr. Kafasla’s research focuses on RNA-processing events and RNA-protein interactions that shape, at the cellular as well as whole animal level, the post-transcriptional control of gene expression in physiological and in disease states, such as inflammatory disease and cancer.
Dr. Koliaraki's research in the lab focuses on the role of mesenchymal-specific innate-immune signaling pathways in animal models of inflammatory bowel disease and inflammation-induced colorectal carcinogenesis.
Lecturers and Research Staff
Dr. Aidinis' research endeavors, currently focus on two pillars: 1) the molecular and genetic dissection of pathogenetic mechanisms in the development of pulmonary inflammation, fibrosis and cancer; 2) the investigation of the role of autotaxin and phospholipid signalling in chronic inflammation and cancer.
KATIA KARALIS (Biomedical Research Foundation of the Academy of Athens)
Dr. Karalis' research focuses on understanding the role of stressful stimuli in the development and pathophysiology of inflammatory diseases and is based on in vitro and in vivo studies using transgenic animal models. The ultimate goal is to identify biomarkers for application to human diseases and evelopment of new therapeutic approaches.
IANNIS TALIANIDIS (BSRC Alexander Fleming)
Dr. Talianidis' interests focus on the molecular mechanisms governing the transcriptional regulation of liver-specific genes. His research is broadly centered around the analysis of the function of hepatic regulators and the general transcription machinery.
NEKTARIOS TAVERNARAKIS (Institute of Molecular Biology and Biotechnology)
Dr. Tavernarakis' lab uses the soil-dwelling, nematode worm Caenorhabditis elegans, to investigate the molecular mechanisms of neuronal function and dysfunction, focusing in the research directions of Ageing & energy metabolism, sensory transduction & integration as well as Neurodegeneration & Necrotic cell death.
Dr. Tsarbopoulos’ research focuses on studying protein conformations and protein-ligand interactions by novel Mass Spectrometry (MS) methodologies. In particular, he has an interest in providing insights in the protein aggregation processes involved in Alzheimer’s Disease (AD), and identifying novel molecules possessing anti-neurodegenerative properties.
EVANGELOS ANDREAKOS (Biomedical Research Foundation of the Academy of Athens)
Dr. Andreakos' research is centered around the impact of innate immunity on the adaptive immune response with special emphasis on the modulation of dendritic cell function, the regulation of T cell polarization, and their role in chronic inflammatory disease.
Dr. Douni's research is focused on the pathogenic mechanisms underlying in RANKL-mediated pathologies such as osteoporosis or osteopetrosis by studying either transgenic mice overexpressing human RANKL or mutant mice carrying a loss-of-function mutation in RANKL gene, respectively.
Dr. Fousteris' research is centred on the molecular mechanisms that couple arrest of active transcription to chromatin alteration and repair in healthy versus disease situations. To delineate these events, we employ advanced proteomics and high-throughput genomic approaches in combination with biochemical and cellular techniques.
Dr. Armaka's research interests are mainly focused on the molecular dissection of the synovial fibroblast behavior in several murine models of inflammatory polyarthritis as well as on the cell-specific role of TNF receptor p55 in physiology and disease.
Dr. Papanikolaou's research interests focus on the: Molecular biology of viruses and/or bacteria, Development of gene therapy approaches and Molecular genetics of inherited diseases.
PANAYOTIS VERGINIS (Biomedical Research Foundation of the Academy of Athens)
Dr. Verginis' primary research interests are in the area of immune regulation with emphasis on the maintenance and re-establishment of immunological tolerance.
Dr. Melagraki's research interests focus on chemoinformatics, nanoinformatics and applied drug and materials design projects. She has a strong scientific background in the field of computational and organic chemistry and she has developed several computational tools.
Dr. Chatzigeorgiou’s research interests lie in mechanisms perturbing the homeostasis of metabolic organs, with special focus on the role of inflammation in the development of obesity-related adipose tissue dysfunction and non-alcoholic steatohepatitis.
Dr. Georgios Pavlopoulos is the Head of Bioinformatics at BSRC Alexander Fleming Institute. His lab consists of bioinformaticians and software engineers trying to create scalable and efficient applications for biological problem solving. The lab mainly focuses on network analysis, data integration and visualization as well as genomics and metagenomics.
Dr. Alexopoulos is Founder and Chief Scientific Advisor of Protat once. He has strong experience in multiplex proteomic assays for drug discovery in both experimental and computational aspects and has collaborated and worked with leading companies in the area of Systems Pharmacology like Pfizer, Vertex and Boehringer Ingelheim.
Dr. Denis is CEO of Biomedcode Hellas SA since 2010, a Contract Research Organization providing full preclinical drug evaluation services using a unique collection of mouse models of human inflammatory diseases mimicking Rheumatoid Arthritis, Intestinal Inflammation, Multiple Sclerosis and others.
Ms. Ikonomidou is a Strategic Business Development consultant and aspiring entrepreneur with substantial experience working with technology based start up companies in the fields of biotechnology and energy. Combination of hands on operations experience as a Manager or CEO with exposure to cutting edge research.
Dr. Karagianni joined Biomedcode's Scientific Management Team, as Chief Scientific Officer in 2009 and head of Biomedcode's Research and Development activities that aim to lead to innovative approaches in field of inflammatory and autoimmune diseases.
Dr. Pandis is a Translational informatics scientist with an aptitude in large-scale healthcare and biomedical research projects. He is utilizing the domain knowledge acquired both as a biomedical scientist and bioinformatician, in the development of advanced informatics solutions to big data challenges in translational research.
Mr. Stangos is the founder and co-founder of innovative and traditional companies and organizations. He is the president and CEO of an integrated communication group of companies MSCOMM. He is also the founder of Industry Disruptors – Game Changers, an ecosystem to enhance entrepreneurship in the Southeast Mediterranean region.
ALEX STRONGILOS (proACTINA SA)
Dr. Strongilos is President & CEO of proACTINA SA a research driven SME company based in Athens-Greece. Its primary goal is to develop innovative products and technologies within the Life Sciences sector and subsequent exploitation of the intellectual property generated.